381) A 32 year old Caucasian man is evaluated in your office for hypertension. He reports that he was first noted to have high blood pressure 6-months ago at which time the reading was 146/92 . At that time, he was asked to follow-up in the office however, he disregarded the advise. Recently, during a pre-employment check-up and again at a community health fair, he was noted to have high blood pressure above 150/90 . He denies any dizziness, chest pain, palpitations or shortness of breath. He does not smoke or does not drink alcohol. His mother was diagnosed with hypertension at 60 years of age and father has had hypertension since the age of 50. He On examination, his blood pressure is 154/98. Body Mass Index is 24kg/m2. Cardiac examination shows regular heart sound with no S3 gallop or S4. There are no audible murmurs. Abdominal examination is benign and there are no audible bruits. Femoral and radial pulses are normal with out any delay. Ophthalmological examination is normal An electrocardiogram is normal with no evidence of left ventricular hypertrophy. Serum creatinine is 1.0mg% and Urinalysis is normal. Which of the following is the most appropriate next step in evaluating his Hypertension?
A) Renal Artery Magnetic Resonance Angiography
B) 24 Hour Urinary Metanephrines
C) Plasma Renin Activity- Aldosterone Ratio
D) Ambulatory Blood Pressure monitoring
E) No additional diagnostic work-up
